end-ofTags: health, heart, ratRelated StoriesHistory of shingle may up risk of heart diseases46 per cent die every year after heart failure: StudyMeeting heart-health goals can help elderly live longer.This system allowed the researchers to strip rat cells while preserving the lining matrix (Photo: AFP)Washington: A miniature human heart has been created in the laboratory from a rat39;s heart in a breakthrough that could one day revolutionise transplants.For years, researchers have used the Langendorff method to remove the heart from an animal in order to introduce fluid through the aorta, the body39;s largest vessel, then into the artery network of a heart.The mini human heart, which was created by introducing human cells into the matrix of a whole rat heart, may make it easier to confirm basic science findings and test potential new heart drugs for safety and efficacy, according to a preliminary study presented at the American Heart Association39;s Basic Cardiovascular Sciences 2017 Scientific Sessions.

This system allowed the researchers to strip rat cells while preserving the lining matrix of the whole heart to repopulate with human cells.In the current study, researchers used a technique called 4-Flow cannulation, which introduces solution not just into the arteries but into the veins39; network of the heart.Unlike the Langendorff perfusion, 4-Flow cannulation enabled the researchers to preserve the circulation within the entire heart to maintain the normal flow and in addition to stimulate the mechanical expansion heart chambers.Researchers used a technique called 4-Flow cannulation, which introduces solution not just into the arteries but into the veins039; network.This method is also used to high pressure flow monitors z 6300 series deliver solutions that strip away cells from the rat heart before introducing the human cells to model a human heart.